Absolute Vital Health

Non-surgical knee pain relief in mylapore

The combination of hyaluronic acid (HA) and platelet-rich plasma (PRP) has emerged as a promising injectable treatment for moderate knee osteoarthritis, potentially harnessing the complementary benefits of both components. HA, a natural constituent of synovial fluid, enhances joint viscosity and lubrication while also exerting anti-inflammatory effects. Although intra-articular HA injections have been shown to alleviate symptoms in mild-to-moderate osteoarthritis, their therapeutic effects are often temporary and do not appear to alter disease progression. PRP, on the other hand, has demonstrated efficacy in reducing pain and inflammation through its high concentration of platelet-derived growth factors, which may also contribute to tissue regeneration. Recent studies suggest that the combined use of PRP and HA offers a synergistic effect, providing greater clinical benefits than either treatment alone. This approach has shown potential in reducing pain and improving joint function for up to six months post-treatment, marking it as a valuable nonsurgical option for patients with mild-to-moderate knee osteoarthritis.

HA injection in knee joint in mylapore

Viscosupplementation is an intra-articular (IA) treatment approach for knee osteoarthritis (OA) that leverages the physiological role of hyaluronan in synovial joints. The primary objectives of this therapy are to restore the viscoelastic properties of synovial hyaluronan, reduce pain, enhance joint mobility, and reestablish hyaluronan’s natural protective functions within the joint. In the short term, its effectiveness is thought to stem from the pain-relieving properties of the elastoviscous fluid injected into the affected joint. Over time, as pain subsides and joint mobility improves, a cascade of physiological responses may be triggered, leading to restoration of the joint function.

PRP injection in knee in mylapore

Platelet-rich plasma (PRP) is an autologous concentrate of platelets and growth factors obtained through centrifugation of the patient’s blood. It has been shown to stimulate chondrocytes, promoting cartilage regeneration and enhancing the biosynthesis of collagen and proteoglycans. Intra-articular PRP injections not only offer pain relief but may also play a role in slowing the progression of osteoarthritis (OA). The growth factors released from activated platelets encourage the proliferation of chondrocytes and mesenchymal stem cells, thereby supporting the synthesis of type II collagen. Additionally, PRP exerts anti-inflammatory and analgesic effects by suppressing pro-inflammatory mediators such as interleukin-1 (IL-1) and reducing nociceptor activation. Meta-analyses have consistently shown that PRP provides superior clinical outcomes compared to other intra-articular therapies. Treatment protocols typically involve one to three injections. Optimal results have been reported in patients aged 51–65 years, those with a lower mechanical axis angle, and individuals with Kellgren–Lawrence (K/L) grade 2 osteoarthritis. Studies also indicate that administering PRP at a concentration of 10 billion platelets in 8 ml volume improves joint function and helps preserve articular cartilage in knee OA patients.

Non-surgical knee pain relief in mylapore

Genicular nerve ablation (GNA) is a safe and effective option for people with knee pain who haven’t found relief from treatments like weight loss, exercise, or medications, and who either can’t have surgery or want to avoid it. This procedure can reduce pain, improve daily function, and boost overall quality of life, with minimal risk of serious side effects.
The process begins with a simple test called a diagnostic block, where a small amount of local anesthetic (lidocaine) is injected near three specific nerves around the knee using X-ray or ultrasound guidance. If this injection gives at least 50% pain relief for 24 hours, the person is considered a good candidate for the actual nerve ablation.
trigger point injection in T Nagar

The treatment can be done in a doctor’s office with just a local anesthetic, or under mild sedation if the patient is anxious. There is no need for full anesthesia. The procedure is usually done by specialists in pain management.

Unlike other treatments that work inside the knee joint (like injections or surgery), GNA works by gently heating and deactivating the three main sensory nerves that carry pain signals from the arthritic knee to the brain. The heat is applied using a special needle tip and is carefully controlled. Since the treatment is done outside the joint, it avoids the risks associated with invasive procedures. There are two types of RFA used, one is conventional RFA, where the temperature used is 70-90deg C for 90s, with smaller area of lesion whereas the other type if Cooled RFA, where 60deg C is used for 150s, with larger size of lesion and more chances of involving the genicular nerve. Cooled RFA can provide long-lasting pain relief, with some studies showing benefits lasting up to two years.

Frequently Asked Questions

What can I expect during a PRP therapy session for knee arthritis?

Before the Procedure

 

  • You may be advised to stop anti-inflammatory medications (like ibuprofen), pain killers, tablets like aspirin, a few days prior, as they can interfere with the effectiveness of PRP
  • You ll be advised good hydration, to consume healthy food and to avoid processed and junk foods atleast one week prior to PRP procedure

 

PRP Procedure

On the day ot procedure, you can have your food, hydrate well and come in loose clothing. The blood will be drawn in our clinic using the same technique as having it drawn for routine lab testing. Around 40-60ml of blood may be needed depending upon your basal platelet count and whether for a single or both knees. It is spun in a special centrifuge to separate its components, and to extract the most concentrated “platelet rich” portion of the plasma. All these are done under sterile conditions and special commercial kits are used for this separation. This process alone takes minimum of 20-30mins.

The knee area is then cleaned with betadine and sterile drape is applied and the extracted PRP is injected into the knee joint under Ultrasound Image Guidance under sterile conditions. Its done under Local Anaesthesia. 

Post PRP protocol

 

  • Rest for the joint for next 48-72hrs
  • Application of ice on the knee joint for 10mins every hour for the next 48hrs.
  • No consumption of over the counter painkillers
  • Physiotherapy to be started 72hrs post injection
  • To see the dr immediately if there is redness, severe pain, fever post injection.

 

You may experience mild swelling, stiffness, or discomfort at the injection site for a day or two. 

Platelets are very small cells in your blood that are involved in the clotting and healing process. When PRP is injected into the damaged area it causes a mild inflammation that triggers a healing cascade. The procedure may not completely eradicate the symptoms or complaints, it may take between 4 to 6 weeks for symptomatic improvement. Depending on your condition, your doctor may recommend 1 to 3 sessions, spaced a few weeks apart.

How can I prevent knee osteoarthritis from getting worse?

Comprehensive Knee Osteoarthritis Management is important in preventing it from getting worse:

Effective management of knee osteoarthritis necessitates a multifaceted approach, with REGENERATIVE THERAPY playing a pivotal role. This advanced therapeutic modality goes beyond merely addressing the symptoms; it actively intervenes in the underlying disease process. By halting the detrimental inflammatory cascade, regenerative therapies like Platelet Rich Plasma therapy, Mesenchymal Stem Cell therapiy (obtained from Bone marrow or Adipose tissue) create an environment conducive to the natural healing and regeneration of damaged cartilage, the crucial protective tissue within the knee joint. This can involve various techniques aimed at stimulating the body's own repair mechanisms.

Furthermore, LUBRICANT INJECTION provides significant symptomatic relief and improves joint function. These injections introduce a viscous, gel-like substance into the knee joint, effectively restoring the frictionless environment essential for smooth movement. By reducing friction between the joint surfaces, lubricant injections demonstrably alleviate knee pain and enhance mobility, contributing to an improved quality of life. These when combined with Regenerative therapies have additive beneficial effects on the joint.

The benefits of regenerative therapy are amplified and sustained through targeted QUADRICEPS STRENGTHENING EXERCISES. The quadriceps muscles, located at the front of the thigh, are critical for stabilizing and supporting the knee joint. A well-designed exercise program focused on strengthening these muscles provides enhanced joint stability, reduces stress on the articular cartilage, and improves overall knee function. Consistency and proper technique are paramount in achieving optimal results from these exercises.

Integral to long-term knee osteoarthritis management are crucial LIFESTYLE MODIFICATIONS. Achieving and maintaining a healthy weight is paramount, as excess body weight places significant additional stress on the knee joints, accelerating cartilage degeneration and exacerbating pain. Avoiding processed and junk foods, which often contribute to inflammation and weight gain, is strongly recommended. Adopting a balanced and nutritious diet rich in anti-inflammatory foods supports overall joint health. Adequate hydration is also essential for maintaining the viscosity of synovial fluid, the natural lubricant within the joint. Embracing these lifestyle modifications empowers individuals to actively participate in managing their condition and improving their long-term well-being.

How effective are arthritis knee pain injections in relieving pain and inflammation?

Platelet-Rich Plasma (PRP) Injections for Osteoarthritis

Platelet-Rich Plasma (PRP) therapy is a regenerative treatment used to manage osteoarthritis by harnessing the body’s natural healing ability. It involves drawing a small amount of the patient’s own blood, concentrating the platelets—rich in growth factors and cytokines—and injecting them into the affected joint. These biological factors help reduce inflammation and promote tissue repair.

  • Duration of Pain Relief: PRP injections typically provide relief lasting 6 to 12 months, with some studies reporting benefits extending up to 18 months in select individuals. The length of relief varies depending on factors such as disease severity, individual response, and the specific PRP formulation and injection technique.

  • Peak Effect: The most noticeable pain reduction is often observed between 3 to 6 months after the injection, as the growth factors begin to exert their anti-inflammatory and regenerative effects within the joint.

Hyaluronic Acid (HA) Injections for Osteoarthritis

Hyaluronic acid injections, also known as viscosupplementation, involve injecting a gel-like substance into the joint. HA is a natural component of synovial fluid that helps lubricate and cushion the joints. In osteoarthritis, both the quality and quantity of hyaluronic acid decline, contributing to joint stiffness and pain.

  • Duration of Pain Relief: Relief from HA injections usually lasts between 4 to 6 months, after which the substance is gradually broken down and cleared from the joint.

  • Peak Effect: Maximum benefit is generally observed between 4 to 12 weeks post-injection, during which HA enhances joint lubrication and shock absorption, thereby reducing pain and improving function.

Combination Therapy: PRP + Hyaluronic Acid

Recent studies suggest that combining PRP with hyaluronic acid may enhance the benefits of either therapy alone. In this approach, HA serves as a carrier or scaffold, helping to retain the PRP-derived growth factors in the joint for a longer period. This prolonged exposure may amplify tissue repair and extend pain relief—potentially up to 18 months in some cases.

  • Mechanism: While HA offers immediate cushioning and lubrication, PRP contributes to long-term healing by stimulating the regeneration of cartilage and reducing inflammation. Together, they provide both short-term symptomatic relief and longer-term functional improvement.